VRTX Vertex Pharmaceuticals Inc
Health Care > Pharmaceuticals, Biotechnology & Life Sciences > Biotechnology > Biotechnology | NASDAQ, LargeCap, BiotechHealthcare | Last Price: 496.83 | 2026-02-27 | Atrp: 2.73
Sat 21 Feb 2026 to Fri 27 Feb 2026: Score 5
| Metric | Previous | New | Change | Interpretation | |
|---|---|---|---|---|---|
| â | Price Book MRQ | 6.3866 | 6.1032 | ▼ -4.44% | Bullish. Lower is better. Closer to 1; less overvalued on assets but improved perception Stock price divided by book value per share for the most recent quarter |
| â | Enterprise Value/Revenue | 9.5517 | 8.7549 | ▼ -8.34% | Bullish. Lower is better. Slight improvement Enterprise value divided by revenue |
| â | Enterprise Value/EBITDA | 23.5565 | 21.7761 | ▼ -7.56% | Bullish. Lower is better. Slight improvement Enterprise value to earnings before interest, taxes, depreciation |
| â | Short Ratio | 3.04 | 2.78 | ▼ -8.55% | Bullish. Lower is better. Slight improvement |
| â | Enterprise Value | $114.63B | $99.97B | ▼ -12.79% | Bearish. Higher is better. Decreased, reflecting lower market cap and possibly debt adjustments Market capitalization plus debt minus cash |
Fri 13 Feb 2026 to Sat 21 Feb 2026: Score 15
| Metric | Previous | New | Change | Interpretation | |
|---|---|---|---|---|---|
| â | Quarterly Earnings Growth YOY | 51% | 331% | ▲ 600% | Bullish. Higher is better. Quarterly earnings growth YOY growth accelerating. Year-over-year growth in quarterly earnings |
| â | Forward PE | 23.8095 | 20.9205 | ▼ -12.13% | Bullish. Lower is better. Moderate improvement Stock price divided by expected future earnings |
| â | Book Value | 68.197 | 73.49 | ▲ 7.76% | Bullish. Higher is better. Slight increase; stock now trades closer to book value Net asset value of the company per share |
| â | Profit Margin | 31.35% | 32.94% | ▲ 5.07% | Bullish. Higher is better. Profit margin growth accelerating. Percentage of revenue that turns into profit |
| â | Gross Profit TTM | $6180.1M | $6440.5M | ▲ 4.21% | Bullish. Higher is better. Slight increase, but margins may be improving Revenue minus cost of goods sold over the trailing twelve months |
| â | EBITDA | $4711.8M | $4866M | ▲ 3.27% | Bullish. Higher is better. Increase in earnings before interest, taxes, depreciation, and amortization; indicates stronger operational cash flow Earnings before interest, taxes, depreciation, and amortization |
| â | Wall Street Target Price | 514.32 | 530.7037 | ▲ 3.19% | Bullish. Higher is better. Higher analyst expectations, pointing to increased optimism for future performance Analysts' consensus target price for the stock |
| â | Return On Equity TTM | 22.31% | 22.54% | ▲ 1.03% | Bullish. Higher is better. Return on equity TTM growth accelerating. Efficiency in generating profits from shareholders' equity |
| â | Revenue TTM | $11723.3M | $12001.3M | ▲ 2.37% | Bullish. Higher is better. Slight top-line expansion Total revenue over the trailing twelve months |
| â | Revenue Per Share TTM | 45.683 | 46.935 | ▲ 2.74% | Bullish. Higher is better. Slight improvement Revenue generated per outstanding share over the trailing twelve months |
| â | Enterprise Value | $113.22B | $114.63B | ▲ 1.25% | Bullish. Higher is better. Increased, reflecting higher market cap and possibly debt adjustments Market capitalization plus debt minus cash |
| â | Enterprise Value/EBITDA | 24.315 | 23.5565 | ▼ -3.12% | Bullish. Lower is better. Slight improvement Enterprise value to earnings before interest, taxes, depreciation |
| â | EPS Estimate Current Year | 19.895 | 19.2028 | ▼ -3.48% | Bearish. Higher is better. Slight decrease; reduced outlook for current year earnings Expected earnings per share this year |
| â | EPS Estimate Next Year | 22.5656 | 21.8961 | ▼ -2.97% | Bearish. Higher is better. Slight lowered expectations for further out Expected earnings per share next year |
| â | Operating Margin TTM | 40.27% | 39.6% | ▼ -1.66% | Bearish. Higher is better. Operating margin TTM growth slowing. Percentage of revenue left after operating expenses |
| â | Price Book MRQ | 6.3209 | 6.3866 | ▲ 1.04% | Bearish. Lower is better. Further to 1; more overvalued on assets but worsened perception Stock price divided by book value per share for the most recent quarter |
| â | Enterprise Value/Revenue | 9.4342 | 9.5517 | ▲ 1.25% | Bearish. Lower is better. Slight decline Enterprise value divided by revenue |
| â | Quarterly Revenue Growth YOY | 111% | 101% | ▼ -13.64% | Bearish. Higher is better. Quarterly revenue growth YOY growth slowing. Year-over-year growth in quarterly revenue |
Fri 06 Feb 2026 to Fri 13 Feb 2026: Score 13
| Metric | Previous | New | Change | Interpretation | |
|---|---|---|---|---|---|
| â | Earnings Per Share | 13.86 | 15.3 | ▲ 10.39% | Bullish. Higher is better. Moderate increase in earnings per share Profit allocated to each outstanding share |
| â | EPS Estimate Next Year | 20.158 | 22.5656 | ▲ 11.94% | Bullish. Higher is better. Moderate raised expectations for further out Expected earnings per share next year |
| â | EPS Estimate Current Year | 18.4339 | 19.895 | ▲ 7.93% | Bullish. Higher is better. Slight increase; improved outlook for current year earnings Expected earnings per share this year |
| â | Price Book MRQ | 6.8931 | 6.3209 | ▼ -8.3% | Bullish. Lower is better. Closer to 1; less overvalued on assets but improved perception Stock price divided by book value per share for the most recent quarter |
| â | Short Ratio | 3.3 | 3.04 | ▼ -7.88% | Bullish. Lower is better. Slight improvement |
| â | Forward PE | 24.0964 | 23.8095 | ▼ -1.19% | Bullish. Lower is better. Slight improvement Stock price divided by expected future earnings |
| â | Enterprise Value/Revenue | 9.8033 | 9.4342 | ▼ -3.77% | Bullish. Lower is better. Slight improvement Enterprise value divided by revenue |
| â | Enterprise Value/EBITDA | 24.6515 | 24.315 | ▼ -1.37% | Bullish. Lower is better. Slight improvement Enterprise value to earnings before interest, taxes, depreciation |
| â | Price Sales TTM | 10.0343 | 10.1701 | ▲ 1.35% | Bearish. Lower is better. Higher multiple; market willing to pay more per dollar of sales Stock price divided by revenue per share over the trailing twelve months |
| â | Enterprise Value | $114.93B | $113.22B | ▼ -1.48% | Bearish. Higher is better. Decreased, reflecting lower market cap and possibly debt adjustments Market capitalization plus debt minus cash |
Fri 30 Jan 2026 to Fri 06 Feb 2026: Score 2
| Metric | Previous | New | Change | Interpretation | |
|---|---|---|---|---|---|
| â | Price Sales TTM | 10.3601 | 10.0343 | ▼ -3.14% | Bullish. Lower is better. Lower multiple; market willing to pay less per dollar of sales Stock price divided by revenue per share over the trailing twelve months |
| â | Price Book MRQ | 6.9687 | 6.8931 | ▼ -1.08% | Bullish. Lower is better. Closer to 1; less overvalued on assets but improved perception Stock price divided by book value per share for the most recent quarter |
| â | Enterprise Value/Revenue | 9.915 | 9.8033 | ▼ -1.13% | Bullish. Lower is better. Slight improvement Enterprise value divided by revenue |
| â | Enterprise Value/EBITDA | 24.9323 | 24.6515 | ▼ -1.13% | Bullish. Lower is better. Slight improvement Enterprise value to earnings before interest, taxes, depreciation |
| â | Earnings Per Share | 14.22 | 13.86 | ▼ -2.53% | Bearish. Higher is better. Slight decline in earnings per share Profit allocated to each outstanding share |
| â | Enterprise Value | $116.24B | $114.93B | ▼ -1.13% | Bearish. Higher is better. Decreased, reflecting lower market cap and possibly debt adjustments Market capitalization plus debt minus cash |
Fri 23 Jan 2026 to Fri 30 Jan 2026: Score 3
| Metric | Previous | New | Change | Interpretation | |
|---|---|---|---|---|---|
| â | Short Ratio | 3.84 | 3.3 | ▼ -14.06% | Bullish. Lower is better. Moderate improvement |
| â | Short Percent | 2.24% | 1.97% | ▼ -12.05% | Bullish. Lower is better. Moderate decrease; still high, potential for squeeze if positive catalysts emerge Percentage of shares sold short |
| â | Wall Street Target Price | 504.04 | 514.32 | ▲ 2.04% | Bullish. Higher is better. Higher analyst expectations, pointing to increased optimism for future performance Analysts' consensus target price for the stock |
| â | Enterprise Value | $112.55B | $116.24B | ▲ 3.28% | Bullish. Higher is better. Increased, reflecting higher market cap and possibly debt adjustments Market capitalization plus debt minus cash |
| â | Forward PE | 23.753 | 24.3309 | ▲ 2.43% | Bearish. Lower is better. Slight decline Stock price divided by expected future earnings |
| â | Price Sales TTM | 10.221 | 10.3601 | ▲ 1.36% | Bearish. Lower is better. Higher multiple; market willing to pay more per dollar of sales Stock price divided by revenue per share over the trailing twelve months |
| â | Price Book MRQ | 6.7557 | 6.9687 | ▲ 3.15% | Bearish. Lower is better. Further to 1; more overvalued on assets but worsened perception Stock price divided by book value per share for the most recent quarter |
| â | Enterprise Value/Revenue | 9.6003 | 9.915 | ▲ 3.28% | Bearish. Lower is better. Slight decline Enterprise value divided by revenue |
| â | Enterprise Value/EBITDA | 24.141 | 24.9323 | ▲ 3.28% | Bearish. Lower is better. Slight decline Enterprise value to earnings before interest, taxes, depreciation |
Wed 14 Jan 2026 to Fri 23 Jan 2026: Score -1
| Metric | Previous | New | Change | Interpretation | |
|---|---|---|---|---|---|
| â | Price Sales TTM | 9.9437 | 10.221 | ▲ 2.79% | Bearish. Lower is better. Higher multiple; market willing to pay more per dollar of sales Stock price divided by revenue per share over the trailing twelve months |
Tue 06 Jan 2026 to Wed 14 Jan 2026: Score -8
| Metric | Previous | New | Change | Interpretation | |
|---|---|---|---|---|---|
| â | Short Ratio | 3.08 | 3.84 | ▲ 24.68% | Bearish. Lower is better. Significant decline |
| â | Short Percent | 1.91% | 2.24% | ▲ 17.28% | Bearish. Lower is better. Moderate increase; still high, potential for squeeze if positive catalysts emerge Percentage of shares sold short |
| â | Price Sales TTM | 9.8153 | 9.9437 | ▲ 1.31% | Bearish. Lower is better. Higher multiple; market willing to pay more per dollar of sales Stock price divided by revenue per share over the trailing twelve months |
| â | Price Book MRQ | 6.6237 | 6.7476 | ▲ 1.87% | Bearish. Lower is better. Further to 1; more overvalued on assets but worsened perception Stock price divided by book value per share for the most recent quarter |
| â | Enterprise Value/Revenue | 9.4053 | 9.5884 | ▲ 1.95% | Bearish. Lower is better. Slight decline Enterprise value divided by revenue |
| â | Enterprise Value/EBITDA | 23.6507 | 24.1111 | ▲ 1.95% | Bearish. Lower is better. Slight decline Enterprise value to earnings before interest, taxes, depreciation |
| â | Wall Street Target Price | 491.9167 | 500.4 | ▲ 1.72% | Bullish. Higher is better. Higher analyst expectations, pointing to increased optimism for future performance Analysts' consensus target price for the stock |
| â | Enterprise Value | $110.26B | $112.41B | ▲ 1.95% | Bullish. Higher is better. Increased, reflecting higher market cap and possibly debt adjustments Market capitalization plus debt minus cash |
Sun 21 Dec 2025 to Tue 06 Jan 2026: Score 2
| Metric | Previous | New | Change | Interpretation | |
|---|---|---|---|---|---|
| â | Price Sales TTM | 9.9772 | 9.8153 | ▼ -1.62% | Bullish. Lower is better. Lower multiple; market willing to pay less per dollar of sales Stock price divided by revenue per share over the trailing twelve months |
| â | Short Percent | 1.98% | 1.91% | ▼ -3.54% | Bullish. Lower is better. Slight decrease; still high, potential for squeeze if positive catalysts emerge Percentage of shares sold short |